Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089845 | 0.84 | TDP1 (0.43) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL3133440 | 0.84 | TDP1 (0.43) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL3457849 | 0.76 | EGFR (0.54) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL8527256 | 0.75 | TDP1 (0.49) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL3130095 | 0.74 | TDP1 (0.48) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL13672568 | 0.73 | TDP1 (0.44) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL23453027 | 0.73 | HTT (0.51) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL30089853 | 0.72 | FLT4 (0.43) | FLT4KDREGFR | |
| SCHEMBL7872820 | 0.70 | HDAC1 (0.48) | FLT4KDREGFRPDE4APDE4B | |
| SCHEMBL1404491 | 0.70 | DAPK1 (0.72) | FLT4KDREGFRPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042349-A1 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999020643-A9 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999020643-A1 | USING POLYAMIDE NUCLEIC ACID OLIGOMERS TO ENGENDER A BIOLOGICAL RESPONSE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-04-29 | — | — | WO | disclosed |