Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130095 | 0.85 | TDP1 (0.48) | HTTRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL27967736 | 0.83 | RAB9A (0.70) | HTTRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL23453066 | 0.81 | TDP1 (0.43) | HTTRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL23453050 | 0.79 | TDP1 (0.40) | HTTTDP1HDAC1HDAC2TMIGD3 | |
| SCHEMBL23453030 | 0.78 | TK1 (0.46) | HTTRAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL1404491 | 0.77 | DAPK1 (0.72) | HTTHPGDADORA2APDE4APDE4B | |
| SCHEMBL23453058 | 0.77 | HDAC1 (0.41) | HTTTDP1HDAC1HDAC2TMIGD3 | |
| SCHEMBL7906492 | 0.77 | PDE4A (0.49) | HTTRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL27967584 | 0.77 | TMIGD3 (0.65) | HTTRAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL24709730 | 0.77 | EGFR (0.65) | HTTRAB9AHPGDNPC1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163541-A1 | Method for Preparing PNA Oligomer | SEASUNBIO MATERIALS (KR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163541-A1 | Method for Preparing PNA Oligomer | NCL, NOD1, POLI | HTT 723/4885RAB9A 4156/4885HPGD 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.