Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527919 | 0.82 | LMNA (0.47) | GAANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3457849 | 0.81 | EGFR (0.54) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8527262 | 0.80 | ALDH1A1 (0.46) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL3130095 | 0.79 | TDP1 (0.48) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3133440 | 0.78 | TDP1 (0.43) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30089845 | 0.78 | TDP1 (0.43) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6748343 | 0.76 | HDAC1 (0.58) | HDAC1NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8056331 | 0.75 | FLT4 (0.45) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24540240 | 0.74 | TDP1 (0.42) | TDP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5962910 | 0.73 | ADORA3 (0.68) | TDP1NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885236-A1 | OLIGONUCLEOTIDE ANALOGS | Codon Pharmaceuticals, Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997027206-A1 | OLIGONUCLEOTIDE ANALOGS | CODON PHARMACEUTICALS, INC. (US) | 1997-07-31 | — | — | WO | disclosed |