Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | GAA | P10253 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 11/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172113 | 0.75 | ALOX12 (0.37) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL9172116 | 0.75 | ALOX12 (0.37) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8054084 | 0.72 | ADRA1D (0.33) | — | |
| SCHEMBL543477 | 0.70 | CYP2A6 (0.43) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3081631 | 0.67 | MEN1 (0.69) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL16218024 | 0.67 | MEN1 (0.69) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL734790 | 0.66 | KMT2A (1.00) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3065879 | 0.66 | MAPT (0.62) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6714200 | 0.66 | MAPT (0.62) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6714202 | 0.66 | MAPT (0.62) | MAPTGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502473-B1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | NOVARTIS AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| US-5384321-A | Benzothiadiazole compounds | CIBA-GEIGY CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| US-5260423-A | Fungicide, viricide or bactericide | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |