Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056516 | 1.00 | ATP6V1B1 (0.54) | ATP6V1B1OPRM1TMEM97SIGMAR1ACKR3 | |
| SCHEMBL8056525 | 1.00 | ATP6V1B1 (0.54) | ATP6V1B1OPRM1TMEM97SIGMAR1ACKR3 | |
| SCHEMBL8053300 | 0.88 | ATP6V1B1 (0.56) | ATP6V1B1KMT2AGAAAPPALDH1A1 | |
| SCHEMBL8053296 | 0.88 | ATP6V1B1 (0.56) | ATP6V1B1KMT2AGAAAPPALDH1A1 | |
| SCHEMBL8053293 | 0.88 | ATP6V1B1 (0.56) | ATP6V1B1KMT2AGAAAPPALDH1A1 | |
| SCHEMBL6291678 | 0.78 | ATP6V1B1 (0.75) | ATP6V1B1ACKR3MEN1CYP2D6KMT2A | |
| SCHEMBL6291675 | 0.78 | ATP6V1B1 (0.75) | ATP6V1B1ACKR3MEN1CYP2D6KMT2A | |
| SCHEMBL6291679 | 0.78 | ATP6V1B1 (0.75) | ATP6V1B1ACKR3MEN1CYP2D6KMT2A | |
| SCHEMBL8038803 | 0.77 | MAPT (0.47) | ATP6V1B1MEN1KMT2AGAAAPP | |
| SCHEMBL8038808 | 0.77 | MAPT (0.47) | ATP6V1B1MEN1KMT2AGAAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025390-A | Heteroaromatic pentadienoic acid derivatives useful as inhibitors of bone resorption | SMITHKLINE BEECHAM SPA (IT) | 2000-02-15 | — | — | US | disclosed |