SCHEMBL80568

SCHEMBL80568

COc1cc(C=C(C(=O)O)c2ccc([N+](=O)[O-])cc2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
GAA P10253 2/20 0.53
HTT P42858 2/20 0.51
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
EGFR P00533 2/20 0.51
GALR2 O43603 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPK1 P28482 1/20 0.51
SYK P43405 1/20 0.51
VCP P55072 1/20 0.51
AKR1C3 P42330 2/20 0.50
POLB P06746 2/20 0.50
KRAS P01116 2/20 0.50
APP P05067 1/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
PTGS2 P35354 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125352 0.84 CXCL12 (0.62) MAPTHTTALDH1A1AKR1C3POLB
SCHEMBL14125351 0.84 CXCL12 (0.62) MAPTHTTALDH1A1AKR1C3POLB
SCHEMBL2951324 0.83 MEN1 (0.62) MAPTGAAHTTEGFRALDH1A1
SCHEMBL2523113 0.83 MEN1 (0.62) MAPTGAAHTTEGFRALDH1A1
SCHEMBL2951322 0.83 MEN1 (0.62) MAPTGAAHTTEGFRALDH1A1
SCHEMBL28461838 0.82 AKR1C3 (0.75) AKR1C3PTGS2
SCHEMBL28899315 0.82 AKR1C3 (0.75) AKR1C3PTGS2
SCHEMBL25278547 0.80 KRAS (0.74) KRASCXCL12
SCHEMBL25198097 0.80 KRAS (0.74) KRASCXCL12
SCHEMBL4254966 0.79 PTGS2 (0.76) MAPTGAAHTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1039 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624376-B2 Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide NOVOZYMES A/S (DK) 2026-05-12 US disclosed
EP-3894551-B1 POLYPEPTIDES HAVING XYLANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES AS (DK) 2026-04-22 EP disclosed
US-12600996-B2 Carbohydrate binding module variants and hybrid polypeptides comprising same NOVOZYMES A/S (DK) 2026-04-14 US disclosed
US-20250270531-A1 GH61 VARIANTS AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2025-08-28 US disclosed
US-12385027-B2 Polypeptides having xylanase activity and polynucleotides encoding same NOVOZYMES A/S (DK) 2025-08-12 US disclosed
US-12331332-B2 GH61 variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2025-06-17 US disclosed
US-20250122545-A1 COMPOSITIONS FOR SACCHARIFICATION OF CELLULOSIC MATERIAL NOVOZYMES, INC. (US) 2025-04-17 US disclosed
US-20250092434-A1 CELLULOLYTIC ENZYME COMPOSITIONS AND USES THEREOF NOVOZYMES, INC. (US) 2025-03-20 US disclosed
US-12234493-B2 Compositions for saccharification of cellulosic material NOVOZYMES, INC. (US) 2025-02-25 US disclosed
US-12195776-B2 Cellulolytic enzyme compositions and uses thereof NOVOZYMES, INC. (US) 2025-01-14 US disclosed
WO-2009127729-A1 POLYPEPTIDES HAVING FERULIC ACID ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2009-10-22 WO disclosed
US-20090162913-A1 FERULATE ESTERASE PRODUCING STRAINS FOR THE ENHANCEMENT OF BIOGAS PRODUCTION PIONEER HI-BRED INTERNATIONAL, INC. 2009-06-25 US disclosed
WO-2009076122-A1 POLYPEPTIDES HAVING FERULOYL ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2009-06-18 WO disclosed
US-20090151026-A1 Polypeptides having feruloyl esterase activity and polynucleotides encoding same NOVOZYMES A/S (DK) 2009-06-11 US disclosed
WO-2009065934-A1 POLYPEPTIDES HAVING FERULIC ACID ESTERASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2009-05-28 WO disclosed
US-20090010903-A1 using ferulate esterase producing bacterial strains or functional mutants thereof as a silage inoculant for improving fiber digestibility; treating pre-ensiled plant material to enhance the digestibility of the resulting silage PIONEER HI-BRED INTERNATIONAL, INC. (US) 2009-01-08 US disclosed
US-20090011085-A1 using ferulate esterase producing bacterial strains or functional mutants thereof as a silage inoculant for improving fiber digestibility; treating pre-ensiled plant material to enhance the digestibility of the resulting silage PIONEER HI-BRED INTERNATIONAL, INC. (US) 2009-01-08 US disclosed
EP-1784085-A1 FERULATE ESTERASE PRODUCING STRAINS AND METHODS OF USING SAME Pioneer-Hi-Bred International, Inc. (US) 2007-05-16 EP disclosed
WO-2006026763-A1 FERULATE ESTERASE PRODUCING STRAINS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2006-03-09 WO disclosed
US-20060046292-A1 using ferulate esterase producing bacterial strains or functional mutants thereof as a silage inoculant for improving fiber digestibility; treating pre-ensiled plant material to enhance the digestibility of the resulting silage PIONEER HI-BRED INTERNATIONAL, INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600996-B2 Carbohydrate binding module variants and hybrid polypeptides comprising same QPCTL, DNTT, RNGTT MAPT 1179/4885GAA 2748/4885HTT 1686/4885
US-12624376-B2 Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide CDC42, RAC1, RAC2 MAPT 3944/4885GAA 4313/4885HTT 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.