Mannitol

Mannitol

SCHEMBL8057003

C=C.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.85
L3MBTL1 Q9Y468 1/20 0.85
TDP1 Q9NUW8 2/20 0.79
KDM4E B2RXH2 2/20 0.52
PDE4A P27815 1/20 0.52
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.37
TOP1 P11387 1/20 0.35
MGAM O43451 2/20 0.33
SI P14410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol SCHEMBL25230964 1.00 LMNA (0.85) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL2990055 1.00 LMNA (0.85) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL27414221 0.96 LMNA (0.79) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2477078 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Sorbitol SCHEMBL763 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL2297640 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL13187369 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594082 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594083 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL23066399 0.92 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127181-A PRECULTURING PLANT CELL WITH DIVALENT CATION AT GREATER THAN 5 MM AND OSMOTIC AGENT TO STABILIZE CELL MEMBRANES; THEN, IN ANY ORDER, APPLYING CRYOPROTECTANT, VITRIFYING WITH CRYOPROTECTANT SOLUTION, AND FREEZING CELLS PHYTON, INC. (US) 2000-10-03 US disclosed
US-5965438-A PRETREATING THE PLANT CELL WITH CRYOPROTECTIVE AGENT AND STABILIZER WHICH IS ANTIOXIDANT OR RADICAL SCAVENGER; THEN IN ANY ORDER, ACCLIMATING CELL TO REDUCED TEMPERATURE, LOADING CELL, VITRIFYING CELL, AND FREEZING TO DESIRED TEMPERATURE PHYTON, INC. (US) 1999-10-12 US disclosed
EP-0830059-A2 CRYOPRESERVATION OF DIVERSE PLANT CELLS PHYTON, INC. (US) 1998-03-25 EP disclosed
WO-1996039812-A2 CRYOPRESERVATION OF DIVERSE PLANT CELLS PHYTON, INC. (US) 1996-12-19 WO disclosed