Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28748807 | 0.95 | LTA4H (0.47) | LTA4HALOX5PPARGPPARAPLA2G4B | |
| SCHEMBL8497121 | 0.78 | LMNA (0.46) | LTA4HDRD2MAOADRD3ALDH1A1 | |
| SCHEMBL9323932 | 0.76 | ALDH1A1 (0.43) | FAAHALDH1A1TP53 | |
| SCHEMBL28843462 | 0.75 | BCL9 (0.47) | FAAHESR1SMN1; SMN2 | |
| SCHEMBL28322019 | 0.75 | BCL9 (0.47) | FAAHESR1SMN1; SMN2 | |
| SCHEMBL4575502 | 0.75 | ZDHHC2 (0.41) | PPARGPPARAFAAHALDH1A1 | |
| SCHEMBL10335587 | 0.74 | SLC2A1 (0.36) | PLA2G4BALDH1A1SLC2A1TP53TSHR | |
| SCHEMBL16399710 | 0.74 | EGFR (0.48) | PPARGPPARAESR1ALDH1A1MAPK1 | |
| SCHEMBL8494781 | 0.74 | LMNA (0.44) | LTA4HDRD2MAOADRD3LMNA | |
| SCHEMBL11871818 | 0.74 | LTA4H (0.49) | LTA4HALOX5PPARGPPARAPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046303-A | MADE BY ADDING DIOXOTETRAHYDROFURAN 3-METHYLCYCLOHEXENE-1,2-DICARBOXYLIC DIANHYDRIDE TO A MIXTURE OF AROMATIC TETRACARBOXYLIC DIANHYDRIDES AND AROMATIC DIAMINES HAVING ALKOXY SIDE CHAINS; FOR LIQUID CRYSTAL ALIGNMENT LAYER | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-04-04 | — | — | US | disclosed |