Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 3/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.44 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559601 | 0.73 | CES1 (0.56) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL8791995 | 0.72 | CES1 (0.54) | LMNAKDM4ETSHRMAPTHTT | |
| SCHEMBL27847333 | 0.71 | LMNA (0.46) | LMNACCR1CCR5CCR8KDM4E | |
| SCHEMBL261907 | 0.69 | CES1 (0.39) | KDM4EMAPTHSP90AA1HIF1AALDH1A1 | |
| Anthracene SCHEMBL28233789 | 0.69 | CES1 (0.39) | KDM4EMAPTHSP90AA1HIF1AALDH1A1 | |
| SCHEMBL1021274 | 0.68 | S100A4 (0.41) | KDM4ETDP1ALDH1A1CA1CA2 | |
| SCHEMBL11946888 | 0.68 | LMNA (0.50) | LMNACCR1CCR5CCR8KDM4E | |
| Hydrochloric Acid SCHEMBL31127657 | 0.67 | S100A4 (0.40) | KDM4ETDP1ALDH1A1CA1CA2 | |
| SCHEMBL19423556 | 0.67 | S100A4 (0.40) | KDM4ETDP1ALDH1A1CA1CA2 | |
| SCHEMBL15405526 | 0.67 | S100A4 (0.40) | KDM4ETDP1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114055-A | Organic electroluminescent device with continuous organic medium containing rubrene | MOTOROLA, INC. (US) | 2000-09-05 | — | — | US | claimed |
| US-6013383-A | Organic electroluminescence device with improved hole transporting material | MOTOROLA, INC. (US) | 2000-01-11 | — | — | US | disclosed |