Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058426 | 1.00 | EPHX1 (0.70) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL8058342 | 0.88 | RAB9A (0.73) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL8058343 | 0.88 | RAB9A (0.73) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL8058760 | 0.85 | EPHX1 (0.67) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL8058763 | 0.85 | EPHX1 (0.67) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL12196154 | 0.83 | NPC1 (1.00) | EPHX1RAB9ANPC1EPHX2ALDH1A1 | |
| SCHEMBL8067568 | 0.83 | EPHX1 (0.73) | EPHX1RAB9ANPC1EPHX2MEN1 | |
| SCHEMBL8067570 | 0.82 | LMNA (0.57) | EPHX1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8067567 | 0.82 | LMNA (0.57) | EPHX1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2751488 | 0.82 | NPC1 (0.97) | EPHX1RAB9ANPC1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |