Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA9 | Q16790 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261669 | 0.87 | CA12 (0.70) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL370611 | 0.81 | KMT2A (0.64) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL458085 | 0.80 | CA12 (1.00) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL6705392 | 0.78 | DDAH1 (0.66) | CA12CA1CA9ALDH1A1MAPK1 | |
| SCHEMBL11478927 | 0.78 | CA12 (0.67) | CA12CA1CA9KMT2AALDH1A1 | |
| SCHEMBL29249691 | 0.74 | KMT2A (0.54) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL368155 | 0.74 | CA12 (0.69) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL27893066 | 0.74 | CA12 (0.69) | CA12CA1CA9KMT2AHSD17B10 | |
| SCHEMBL17281692 | 0.73 | MGLL (0.65) | CA12CA1CA9KMT2AALDH1A1 | |
| SCHEMBL8965241 | 0.73 | HSP90AA1 (0.65) | CA12CA1CA9KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000081-A2 | A REVERSIBLE STOICHIOMETRIC PROCESS FOR CONJUGATING BIOMOLECULES | KÖSTER, Hubert (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998033808-A2 | A REVERSIBLE STOICHIOMETRIC PROCESS FOR CONJUGATING BIOMOLECULES | KOSTER HUBERT (US) | 1998-08-06 | — | — | WO | disclosed |
| US-5410068-A | Protecting groups for natural products | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1995-04-25 | — | — | US | disclosed |