Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782968 | 0.74 | ALDH1A1 (0.43) | ALDH1A1ESR1HTT | |
| SCHEMBL3257322 | 0.69 | NPSR1 (0.44) | TRPM8ALDH1A1TSHRHTT | |
| SCHEMBL1244502 | 0.68 | TSHR (0.39) | ALDH1A1TSHRAKR1C3AKR1C1PTGS2 | |
| SCHEMBL8048320 | 0.68 | ALDH1A1 (0.36) | TRPM8ALDH1A1TSHRAKR1C3AKR1C1 | |
| SCHEMBL2390372 | 0.67 | NPSR1 (0.43) | TRPM8ALDH1A1TSHRHTT | |
| SCHEMBL2543854 | 0.67 | TSHR (0.45) | ALDH1A1TSHRAKR1C3ESR1AKR1C1 | |
| SCHEMBL8913897 | 0.67 | TSHR (0.45) | ALDH1A1TSHRAKR1C3AKR1C1HTT | |
| SCHEMBL9560753 | 0.66 | NPSR1 (0.41) | TRPM8ALDH1A1TSHRESR1HTT | |
| SCHEMBL11883850 | 0.66 | AKT1 (0.43) | TRPM8ALDH1A1TSHRHTT | |
| SCHEMBL273919 | 0.66 | KMT2A (0.46) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086764-A | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | CROSSWINDS, INC. (US) | 2000-07-11 | — | — | US | claimed |
| EP-0884096-A1 | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | Crosswinds, Inc. (US) | 1998-12-16 | — | — | EP | claimed |
| US-4584103-A | REACTING WITH HYDROXYLAMINE, THEN DIFUNCTIONAL COMPOUND AND COMPOUND CONTAINING IONIZABLE GROUP | ALIGENA AG (CH) | 1986-04-22 | — | — | US | disclosed |