Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 5/20 | 0.40 |
| ▸ | GLI1 | P08151 | 2/20 | 0.40 |
| ▸ | GLI2 | P10070 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8074658 | 0.90 | MC4R (0.40) | NPY1RTACR1HTR2AHRH1CA12 | |
| SCHEMBL8126608 | 0.89 | TDP1 (0.41) | NPY1RNPFFR1NPFFR2NPY5RHTR2A | |
| SCHEMBL8073016 | 0.87 | CNR1 (0.41) | TACR1HTR2AHRH1CNR1 | |
| Hydrochloric Acid SCHEMBL8069315 | 0.86 | NPY1R (0.43) | NPY1RNPY5R | |
| Hydrochloric Acid SCHEMBL8074403 | 0.86 | ALDH1A1 (0.43) | KDM4ECNR1CNR2 | |
| SCHEMBL1718512 | 0.86 | NPY1R (0.42) | NPY1RGLI1GLI2NPFFR1NPFFR2 | |
| SCHEMBL8072860 | 0.86 | EPOR (0.37) | TACR1 | |
| SCHEMBL8119409 | 0.85 | EPOR (0.43) | NPY1RNPFFR1NPFFR2NPY5RCNR1 | |
| Hydrochloric Acid SCHEMBL8070263 | 0.85 | MC4R (0.42) | TACR1CA12CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL8120628 | 0.83 | EPOR (0.41) | NPY1RNPFFR1NPFFR2NPY5RCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |