Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058896 | 0.87 | NPY1R (0.40) | CNR1TACR1HTR2AHRH1 | |
| SCHEMBL8650060 | 0.86 | TDP1 (0.41) | HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL8074658 | 0.86 | MC4R (0.40) | TACR1HTR2AHRH1 | |
| SCHEMBL8069355 | 0.85 | CNR1 (0.47) | CNR1 | |
| Hydrochloric Acid SCHEMBL8069315 | 0.83 | NPY1R (0.43) | — | |
| Hydrochloric Acid SCHEMBL8074403 | 0.83 | ALDH1A1 (0.43) | CNR1 | |
| SCHEMBL8072860 | 0.82 | EPOR (0.37) | TACR1 | |
| Hydrochloric Acid SCHEMBL8070263 | 0.82 | MC4R (0.42) | TACR1 | |
| SCHEMBL8072950 | 0.81 | FOLH1 (0.46) | CNR1 | |
| SCHEMBL8126608 | 0.80 | TDP1 (0.41) | CNR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |