Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8074403 | 0.89 | ALDH1A1 (0.43) | EPORSMN1; SMN2KMT2AALDH1A1EPHX1 | |
| SCHEMBL8058896 | 0.86 | NPY1R (0.40) | TACR1 | |
| Hydrochloric Acid SCHEMBL8074658 | 0.85 | MC4R (0.40) | TACR1ALDH1A1 | |
| SCHEMBL8073016 | 0.82 | CNR1 (0.41) | TACR1 | |
| Hydrochloric Acid SCHEMBL8070263 | 0.82 | MC4R (0.42) | TACR1 | |
| Hydrochloric Acid SCHEMBL8069315 | 0.81 | NPY1R (0.43) | KMT2APOLB | |
| SCHEMBL8127789 | 0.80 | TDP1 (0.46) | EPORNPC1RAB9ASMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL8074521 | 0.78 | CNR2 (0.33) | — | |
| SCHEMBL8058871 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2KMT2APOLBALDH1A1EPHX1 | |
| SCHEMBL8650060 | 0.76 | TDP1 (0.41) | EPORKMT2AALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |