Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413794 | 0.94 | ALDH1A1 (0.36) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3849517 | 0.89 | KDM4E (0.34) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL6450077 | 0.83 | MEN1 (0.36) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3853401 | 0.83 | KDM4E (0.35) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3851010 | 0.83 | ADRB2 (0.37) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL4449490 | 0.78 | — | — | |
| SCHEMBL4425462 | 0.74 | P2RX7 (0.40) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3850149 | 0.73 | HSD17B10 (0.42) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL5189897 | 0.73 | HSD17B10 (0.45) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL3851899 | 0.73 | P2RX7 (0.38) | ALDH1A1KDM4EKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006390-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |