Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070266 | 0.93 | MAPT (0.53) | TAS2R14MAPTPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL8073072 | 0.91 | MAPT (0.54) | TAS2R14MAPTPOLBLMNATP53 | |
| SCHEMBL8073250 | 0.90 | TAS2R14 (0.61) | TAS2R14MAPTALDH1A1HTTNPSR1 | |
| SCHEMBL8071658 | 0.87 | MAPT (0.56) | TAS2R14MAPTPOLBLMNATP53 | |
| SCHEMBL8070249 | 0.87 | MAPT (0.49) | TAS2R14MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8070407 | 0.87 | MAPT (0.51) | TAS2R14MAPTLMNA | |
| SCHEMBL8059182 | 0.86 | TAS2R14 (0.54) | TAS2R14MAPTALDH1A1LMNA | |
| SCHEMBL8059343 | 0.85 | TP53 (0.49) | TAS2R14MAPTPOLBLMNATP53 | |
| SCHEMBL8069707 | 0.85 | PTPN1 (0.50) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL8059119 | 0.79 | MAPT (0.59) | TAS2R14MAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |