Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070266 | 0.90 | MAPT (0.53) | MAPTTP53CYP2C9POLBKMT2A | |
| SCHEMBL8073072 | 0.89 | MAPT (0.54) | MAPTTHRBTP53POLBLMNA | |
| SCHEMBL8083933 | 0.88 | MAPT (0.51) | MAPTTHRBTP53PSEN1PSEN2 | |
| SCHEMBL8071658 | 0.88 | MAPT (0.56) | MAPTTHRBTP53CYP2C9POLB | |
| SCHEMBL8070407 | 0.87 | MAPT (0.51) | MAPTLMNATAS2R14 | |
| SCHEMBL8059294 | 0.87 | TAS2R14 (0.53) | MAPTTHRBTP53ALDH1A1POLB | |
| SCHEMBL8059182 | 0.86 | TAS2R14 (0.54) | MAPTALDH1A1LMNATAS2R14CXCR3 | |
| SCHEMBL8074805 | 0.85 | MAPT (0.53) | MAPTTHRBTP53POLBKMT2A | |
| SCHEMBL8069707 | 0.85 | PTPN1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL8059343 | 0.82 | TP53 (0.49) | MAPTTP53POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |