SCHEMBL8069707

SCHEMBL8069707

Cc1cc(S(=O)(=O)N(Cc2ccccc2)Cc2ccccc2)ccc1C(=O)COC(=O)Nc1ccc(C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 0.50
MAPT P10636 3/20 0.48
MTOR P42345 1/20 0.45
MGLL Q99685 1/20 0.43
CNR2 P34972 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
CA9 Q16790 2/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8070266 0.91 MAPT (0.53) PTPN1MAPTCNR2
SCHEMBL8070407 0.90 MAPT (0.51) PTPN1MAPTCNR2
SCHEMBL8073072 0.90 MAPT (0.54) MAPTCNR2
SCHEMBL8059182 0.88 TAS2R14 (0.54) MAPTCNR2ALDH1A1
SCHEMBL8064181 0.87 MAPT (0.54) PTPN1MAPTMTORCNR2ALDH1A1
SCHEMBL8071658 0.87 MAPT (0.56) PTPN1MAPT
SCHEMBL8070249 0.85 MAPT (0.49) MAPTALDH1A1
SCHEMBL8059294 0.85 TAS2R14 (0.53) MAPTCA12CA1CA2CA4
SCHEMBL8059343 0.83 TP53 (0.49) PTPN1MAPT
SCHEMBL8074725 0.78 MAPT (0.63) MAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1017685-A1 NEW 2-(3H)-OXAZOLONE DERIVATIVES ALMIRALL-PRODESFARMA, S.A. (ES) 2000-07-12 EP disclosed
WO-1999014205-A1 NEW 2-(3H)-OXAZOLONE DERIVATIVES ALMIRALL PRODESFARMA S.A. (ES) 1999-03-25 WO disclosed