Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL1637663 | 0.90 | THRB (0.35) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL2701657 | 0.90 | THRB (0.35) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL16653852 | 0.87 | THRB (0.39) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL16399244 | 0.87 | THRB (0.40) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL111075 | 0.87 | THRB (0.41) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL29155230 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Methacrylic Acid SCHEMBL6740567 | 0.85 | THRB (0.32) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL4147380 | 0.85 | THRB (0.40) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL7788195 | 0.85 | THRB (0.40) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL15789440 | 0.84 | THRB (0.43) | THRBALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273274-B1 | Degradation of polyethylene by means of agents generating free radicals | ATOCHEM ELF DEUTSCHLAND (DE) | 2000-07-12 | — | — | EP | disclosed |
| EP-0273274-A2 | Degradation of polyethylene by means of agents generating free radicals | Elf Atochem Deutschland GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |
| EP-0073038-A1 | Process for cross-linking and if required foaming natural or synthetic homo- and/or copolymers | Luperox GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |