Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL1637663 | 0.94 | THRB (0.35) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL2701657 | 0.94 | THRB (0.35) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL28074211 | 0.90 | THRB (0.31) | THRB | |
| Methacrylic Acid SCHEMBL29155230 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL11582719 | 0.86 | THRB (0.38) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL29150520 | 0.86 | ALDH1A1 (0.34) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL8059435 | 0.85 | THRB (0.40) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL27869348 | 0.85 | THRB (0.33) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL28072794 | 0.82 | TGFBR1 (0.31) | — | |
| Methacrylic Acid SCHEMBL9007731 | 0.82 | TGFBR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6682750-B2 | CROSSLINKED WATER-SOLUBLE OR WATER-SWELLABLE COPOLYMERS BASED ON ACRYLAMIDOALKYLSULFONIC ACIDS AND CYCLIC N-VINYLCARBOXAMIDES | CLARIANT GMBH (DE) | 2004-01-27 | — | — | US | disclosed |