Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.34 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068459 | 0.86 | SCN9A (0.36) | LMNAMAPK1HTR2ASLC6A4LPAR1 | |
| SCHEMBL8070202 | 0.86 | SCN9A (0.39) | LMNAMAPK1HTR2ASLC6A4LPAR1 | |
| SCHEMBL8070508 | 0.83 | LPAR1 (0.39) | LMNAHTR2ASLC6A4LPAR1LPAR5 | |
| SCHEMBL8059454 | 0.82 | HTR2A (0.38) | HTR2ASLC6A4LPAR1LPAR5HRH3 | |
| SCHEMBL8059455 | 0.74 | HRH3 (0.40) | HTR2ASLC6A4HRH3TAAR5TAAR1 | |
| Hydrochloric Acid SCHEMBL8073473 | 0.74 | THRA (0.36) | LPAR1LPAR5 | |
| SCHEMBL8074970 | 0.72 | SLC6A2 (0.45) | SLC6A4LPAR1LPAR5HRH3FFAR1 | |
| SCHEMBL8059397 | 0.72 | THRA (0.42) | LMNASLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL8070331 | 0.72 | SLC6A2 (0.44) | SLC6A4LPAR1LPAR5HRH3FFAR1 | |
| SCHEMBL8059495 | 0.72 | THRA (0.41) | LMNASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |