Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8073473 | 0.89 | THRA (0.36) | BMP1THRATHRBF10PRSS1 | |
| SCHEMBL8059451 | 0.86 | LMNA (0.38) | LMNAMAPK1HTR2ASLC6A4ACACB | |
| SCHEMBL8068838 | 0.84 | ALDH1A1 (0.41) | SCN9ALMNAALDH1A1BMP1THRA | |
| SCHEMBL8059376 | 0.84 | SCN9A (0.44) | SCN9ALMNAALDH1A1HTTKMT2A | |
| SCHEMBL8059397 | 0.84 | THRA (0.42) | LMNASLC6A4BMP1THRATHRB | |
| SCHEMBL8070202 | 0.83 | SCN9A (0.39) | SCN9ALMNAMAPK1HTR2ASLC6A4 | |
| SCHEMBL8068470 | 0.83 | — | — | |
| SCHEMBL8059495 | 0.83 | THRA (0.41) | LMNASLC6A4BMP1THRATHRB | |
| SCHEMBL8070524 | 0.81 | FLT1 (0.42) | SCN9A | |
| SCHEMBL8074945 | 0.81 | F10 (0.35) | SCN9ALMNAMAPK1ALDH1A1BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |