Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068838 | 0.84 | ALDH1A1 (0.41) | LPAR1HRH3LPAR5FFAR1LMNA | |
| SCHEMBL8070159 | 0.84 | FFAR1 (0.42) | LPAR1HRH3LPAR5FFAR1MAPT | |
| SCHEMBL8059451 | 0.83 | LMNA (0.38) | LPAR1HRH3LPAR5FFAR1HTR2A | |
| SCHEMBL8059454 | 0.83 | HTR2A (0.38) | LPAR1HRH3LPAR5FFAR1HTR2A | |
| SCHEMBL8331820 | 0.72 | GAA (0.53) | MAPTRAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL8073466 | 0.72 | BMP1 (0.40) | LPAR1HRH3LPAR5SLC6A4 | |
| SCHEMBL7347897 | 0.70 | SIGMAR1 (0.43) | NPC1MAPTCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL7942139 | 0.69 | ALDH1A1 (0.55) | FFAR1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8068459 | 0.69 | SCN9A (0.36) | LPAR1LPAR5HTR2ASMN1; SMN2LMNA | |
| SCHEMBL8068627 | 0.69 | LPAR1 (0.48) | LPAR1LPAR5FFAR1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |