Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445996 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CYP2C9LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8070565 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP2C9LMNAKMT2A | |
| SCHEMBL8059494 | 0.82 | ALDH1A1 (0.51) | ALDH1A1CYP2C9LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8073733 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CYP2C9LMNAKMT2ATSHR | |
| SCHEMBL11052251 | 0.72 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8445993 | 0.70 | ALDH1A1 (0.48) | ALDH1A1CYP2C9LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9436788 | 0.69 | MAPT (0.58) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8070562 | 0.69 | ALDH1A1 (0.47) | ALDH1A1CYP2C9LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8446349 | 0.69 | SLC9A1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL8059477 | 0.68 | SLC9A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | claimed |
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |