Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8070565 | 0.99 | ALDH1A1 (0.48) | ALDH1A1SLC9A1CYP3A4CYP2C9LMNA | |
| SCHEMBL8059504 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP2C9LMNAKMT2A | |
| SCHEMBL8445993 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP2C9LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8070562 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CYP2C9LMNAKMT2A | |
| SCHEMBL8070200 | 0.78 | CCR2 (0.49) | SLC9A1CYP3A4CYP2C9KMT2AKCNH2 | |
| SCHEMBL8767706 | 0.78 | SLC9A1 (0.53) | SLC9A1CYP3A4CYP2C9ADRA1DHTR2A | |
| SCHEMBL8068662 | 0.77 | CCR2 (0.50) | SLC9A1CYP3A4CYP2C9KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL8505886 | 0.77 | SLC9A1 (0.52) | SLC9A1CYP3A4CYP2C9ADRA1DHTR2A | |
| Hydrochloric Acid SCHEMBL8506601 | 0.76 | SLC9A1 (0.52) | SLC9A1CYP3A4CYP2C9ADRA1DHTR2A | |
| Hydrochloric Acid SCHEMBL8503964 | 0.75 | SLC9A1 (0.49) | SLC9A1CYP3A4CYP2C9ADRA1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | claimed |
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |