Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | DCK | P27707 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174603 | 0.81 | SLC6A2 (0.32) | HTR1ASLC6A2 | |
| SCHEMBL8062064 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAP4K4ALDH1A1LMNA | |
| SCHEMBL8176365 | 0.80 | SMN1; SMN2 (0.53) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 | |
| SCHEMBL468017 | 0.76 | MAP4K4 (0.47) | MAP4K4ALDH1A1SMN1; SMN2DCK | |
| SCHEMBL17764755 | 0.76 | MEN1 (0.45) | MEN1KMT2AMRGPRX1ALDH1A1KDM4E | |
| SCHEMBL6773239 | 0.75 | SMN1; SMN2 (0.47) | MEN1KMT2AMAP4K4ALDH1A1MAPT | |
| SCHEMBL16541082 | 0.75 | MEN1 (0.53) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 | |
| SCHEMBL12825388 | 0.71 | MEN1 (0.49) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 | |
| SCHEMBL307909 | 0.71 | MEN1 (0.49) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 | |
| SCHEMBL2044641 | 0.70 | MEN1 (0.59) | MEN1KMT2AMAP4K4MRGPRX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015412-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-1015420-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| US-6075148-A | CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| US-5981532-A | FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| WO-1999012892-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| WO-1999012885-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |