SCHEMBL8174603

SCHEMBL8174603

Fc1cccc(F)c1Oc1c[c]ncn1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.32
HTR1A P08908 1/20 0.32
SLC6A4 P31645 1/20 0.32
CHRM4 P08173 1/20 0.31
GCK P35557 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8059604 0.81 MEN1 (0.47) SLC6A2HTR1A
SCHEMBL17764755 0.74 MEN1 (0.45)
SCHEMBL2752152 0.72 SLC6A2 (0.35) SLC6A2HTR1ASLC6A4GCK
SCHEMBL971463 0.70 GCK (0.40) SLC6A2HTR1ASLC6A4GCK
SCHEMBL7754263 0.70 L3MBTL1 (0.37)
SCHEMBL2752156 0.68 SLC6A2 (0.33) SLC6A2HTR1ASLC6A4CHRM4
SCHEMBL7759150 0.68 MAP4K4 (0.40)
SCHEMBL8062064 0.68 ALDH1A1 (0.47) SLC6A2HTR1ASLC6A4
SCHEMBL8176365 0.68 SMN1; SMN2 (0.53) SLC6A2SLC6A4
SCHEMBL16415975 0.67 SLC6A2 (0.45) SLC6A2HTR1ASLC6A4GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6075148-A CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES BASF AKTIENGESELLSCHAFT (DE) 2000-06-13 US disclosed
US-5981532-A FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed