SCHEMBL468017

SCHEMBL468017

N#Cc1ccccc1Oc1c[c]ncn1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.47
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
MAPK14 Q16539 3/20 0.40
PIN1 Q13526 2/20 0.37
ALDH1A1 P00352 1/20 0.37
DCK P27707 1/20 0.35
GCK P35557 1/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
LRRK2 Q5S007 1/20 0.34
SLC22A12 Q96S37 1/20 0.34
ACHE P22303 1/20 0.34
KDR P35968 1/20 0.33
TEK Q02763 1/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
ERBB3 P21860 1/20 0.33
ERBB4 Q15303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24507690 0.79 MAP4K4 (0.56) MAP4K4GAAPOLBMAPK14PIN1
SCHEMBL8176365 0.76 SMN1; SMN2 (0.53) MAP4K4GAAALDH1A1SMN1; SMN2
SCHEMBL8059604 0.76 MEN1 (0.47) MAP4K4ALDH1A1DCKSMN1; SMN2
SCHEMBL8062064 0.76 ALDH1A1 (0.47) MAP4K4ALDH1A1
SCHEMBL28100319 0.75 MAPK14 (0.49) MAP4K4GAAPOLBMAPK14PIN1
SCHEMBL7173106 0.73 MAP4K4 (0.50) MAP4K4GAAPOLBMAPK14PIN1
SCHEMBL16202033 0.73 MAP4K4 (0.50) MAP4K4GAAPOLBPIN1ALDH1A1
SCHEMBL7173109 0.73 MAP4K4 (0.50) MAP4K4GAAPOLBMAPK14PIN1
SCHEMBL10049643 0.73 MAP4K4 (0.50) MAP4K4GAAPOLBMAPK14PIN1
SCHEMBL30449029 0.73 MAP4K4 (0.50) MAP4K4GAAPOLBMAPK14PIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278445-B2 Preparation methods of azoxystrobin and its analogs NUTRICHEM COMPANY LIMITED (CN) 2012-10-02 US claimed
EP-2385762-A2 PESTICIDAL MIXTURES BASF SE (DE) 2011-11-16 EP claimed
US-20110269628-A1 Pesticidal Mixtures BASF SE (DE) 2011-11-03 US claimed
US-20100179320-A1 PREPARATION METHODS OF AZOXYSTROBIN AND ITS ANALOGS NUTRICHEM COMPANY LIMITED (CN) 2010-07-15 US claimed
WO-2010079176-A2 PESTICIDAL MIXTURES BASF SE (DE) 2010-07-15 WO claimed
EP-0642735-A1 Fungicidal mixtures BASF Aktiengesellschaft (DE) 1995-03-15 EP claimed
CN-102271510-B Pesticidal mixtures BASF SE (DE) 2014-10-22 CN disclosed
US-8278445-B2 Preparation methods of azoxystrobin and its analogs NUTRICHEM COMPANY LIMITED (CN) 2012-10-02 US disclosed
CN-102271510-A Pesticidal mixtures 2011-12-07 CN disclosed
EP-2385762-A2 PESTICIDAL MIXTURES BASF SE (DE) 2011-11-16 EP disclosed
EP-2385762-A2 PESTICIDAL MIXTURES BASF SE (DE) 2011-11-16 EP disclosed
US-20110269628-A1 Pesticidal Mixtures BASF SE (DE) 2011-11-03 US disclosed
US-20110269628-A1 Pesticidal Mixtures BASF SE (DE) 2011-11-03 US disclosed
EP-0797386-A1 FUNGICIDAL MIXTURE BASF AKTIENGESELLSCHAFT (DE) 1997-10-01 EP disclosed
WO-1997000611-A1 LONG SHELF-LIFE AQUEOUS FUNGICIDAL FORMULATION BASF AKTIENGESELLSCHAFT (DE) 1997-01-09 WO disclosed
US-5591747-A Fungicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
US-5589479-A SYNERGISTIC BASF AKTIENGESELLSCHAFT (DE) 1996-12-31 US disclosed
WO-1996018299-A1 FUNGICIDAL MIXTURE BASF AKTIENGESELLSCHAFT (DE) 1996-06-20 WO disclosed
US-5508283-A SYNERGISTIC BASF AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
EP-0642735-A1 Fungicidal mixtures BASF Aktiengesellschaft (DE) 1995-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179320-A1 PREPARATION METHODS OF AZOXYSTROBIN AND ITS ANALOGS FBL, CA7, SI MAP4K4 3410/4885GAA 951/4885POLB 1024/4885
US-20110269628-A1 Pesticidal Mixtures CNPY2, CNPY3, CBR3 MAP4K4 2673/4885GAA 2220/4885POLB 3784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.