Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.80 |
| ▸ | TSHR | P16473 | 6/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.80 |
| ▸ | HTR2B | P41595 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL6828443 | 0.93 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL301493 | 0.93 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL1619083 | 0.93 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL3003404 | 0.93 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL229 | 0.93 | HSD17B10 (1.00) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL28179668 | 0.90 | HSD17B10 (0.80) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL27893353 | 0.90 | HSD17B10 (0.80) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL27876646 | 0.90 | HSD17B10 (0.80) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL27542315 | 0.90 | HSD17B10 (0.80) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| Diphenylamine SCHEMBL28106450 | 0.90 | HSD17B10 (0.80) | HSD17B10ALDH1A1TDP1TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526805-A | A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application | SHANGHAI INST TECH | 2019-12-03 | — | — | CN | claimed |
| CN-110240539-A | A kind of fluorine substituted diphenylamine ethane compound and preparation method and application | 上海应用技术大学 | 2019-09-17 | — | — | CN | claimed |
| CN-109641935-A | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | 莫拉利达尔·瑞迪·穆拉 | 2019-04-16 | — | — | CN | claimed |
| CN-101022835-A | Antibody conjugated cyanine dyes for the diagnosis of micrometastasis | BAYER SCHERING PHARMA AG (DE) | 2007-08-22 | — | — | CN | claimed |
| EP-0674232-B1 | Recording sheets | XEROX CORP (US) | 2000-05-31 | — | — | EP | claimed |
| EP-0188150-A1 | Process for the preparation of optical isomers of thiazolo[3,2-a]pyrimidines, isomers, pharmaceutical compositions containing them and intermediates for this process | RHONE-POULENC SANTE (FR) | 1986-07-23 | — | — | EP | claimed |
| CN-110526805-A | A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application | SHANGHAI INST TECH | 2019-12-03 | — | — | CN | disclosed |
| CN-110526805-A | A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application | SHANGHAI INST TECH | 2019-12-03 | — | — | CN | disclosed |
| CN-110526805-A | A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application | SHANGHAI INST TECH | 2019-12-03 | — | — | CN | disclosed |
| CN-110240539-A | A kind of fluorine substituted diphenylamine ethane compound and preparation method and application | 上海应用技术大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-110240539-A | A kind of fluorine substituted diphenylamine ethane compound and preparation method and application | 上海应用技术大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-110240539-A | A kind of fluorine substituted diphenylamine ethane compound and preparation method and application | 上海应用技术大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-107365248-A | Diphenylethane and trans stilbene derivative of difluoro-methoxy substitution and its preparation method and application | 上海应用技术大学 | 2017-11-21 | — | — | CN | disclosed |
| CN-1109050-A | Catecholamine surrogates useful as beta3 agonists | BRISTOL MYERS SQUIBB CO (US) | 1995-09-27 | — | — | CN | disclosed |
| CN-1080919-A | As ACAT inhibitors, new N-aryl and N-heteroaryl-ureas analog derivative | PFIZER (US) | 1994-01-19 | — | — | CN | disclosed |
| CN-1051733-A | Acyl-CoA: cholesteryl transferase inhibitor | WARNER LAMBERT CO (US) | 1991-05-29 | — | — | CN | disclosed |
| CN-1050376-A | Acyl-CoA: cholesterol acyltransferase inhibitor | WARBER LAMBERT CO (US) | 1991-04-03 | — | — | CN | disclosed |
| CN-1044813-A | CALCIUM ANTAGONISTS | MERRELL DOW PHARMA (US) | 1990-08-22 | — | — | CN | disclosed |
| EP-0188150-A1 | Process for the preparation of optical isomers of thiazolo[3,2-a]pyrimidines, isomers, pharmaceutical compositions containing them and intermediates for this process | RHONE-POULENC SANTE (FR) | 1986-07-23 | — | — | EP | disclosed |
| US-3991043-A | Quaternization of benzthiazole-azo compounds | TOMS RIVER CHEMICAL CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |