Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 7/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434319 | 0.76 | AKR1C3 (0.48) | AKR1C3ALDH1A1POLBKMT2AMTNR1A | |
| SCHEMBL23846651 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MEN1POLBKMT2AMTNR1A | |
| SCHEMBL296620 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1POLBKMT2ANPSR1 | |
| SCHEMBL9395099 | 0.71 | AKR1C3 (0.44) | AKR1C3ALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL9395086 | 0.71 | AKR1C3 (0.44) | AKR1C3ALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL8060943 | 0.70 | HDAC3 (0.41) | ALDH1A1MEN1POLBKMT2ANPSR1 | |
| Styrene SCHEMBL9054563 | 0.70 | AKR1C3 (0.47) | AKR1C3ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL273919 | 0.69 | KMT2A (0.46) | ALDH1A1MEN1POLBKMT2AMTNR1A | |
| SCHEMBL8439572 | 0.69 | AKR1C3 (0.42) | AKR1C3ALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL23957555 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MEN1POLBKMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086764-A | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | CROSSWINDS, INC. (US) | 2000-07-11 | — | — | US | claimed |
| EP-0884096-A1 | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | Crosswinds, Inc. (US) | 1998-12-16 | — | — | EP | claimed |