SCHEMBL8060339

SCHEMBL8060339

c1cn(N2CCOCC2)cn1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.36
QPCT Q16769 1/20 0.36
HSD17B10 Q99714 1/20 0.36
QPCTL Q9NXS2 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP17A1 P05093 1/20 0.33
HTT P42858 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
ALOX12 P18054 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL7489522 0.94 CYP1A2 (0.33) NFKB1QPCTHSD17B10QPCTLCYP1A2
SCHEMBL540364 0.79 NFKB1 (0.35) NFKB1QPCTHSD17B10QPCTLCYP1A2
SCHEMBL1268157 0.77 CYP2B6 (0.35) NFKB1QPCTHSD17B10QPCTLCYP1A2
SCHEMBL21490423 0.77 CYP2B6 (0.35) NFKB1QPCTHSD17B10QPCTLCYP1A2
Hydrochloric Acid SCHEMBL8473908 0.77 NFKB1 (0.33) NFKB1QPCTHSD17B10QPCTL
SCHEMBL8129527 0.74 ADRB2 (0.36) NFKB1QPCTHSD17B10QPCTLKDM4E
SCHEMBL21047582 0.71 CYP11B1 (0.33) QPCT
Pyrimidine SCHEMBL28401409 0.69 CYP1A2 (0.32) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL1412677 0.69 NFKB1 (0.47) NFKB1QPCTHSD17B10QPCTLCYP3A4
SCHEMBL28873238 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1760347-A Power transmission fluids with enhanced antishudder durability AFTON CHEMICAL CORP (US) 2006-04-19 CN claimed
WO-2021036239-A1 PHOSPHORUS-FREE CLEANING AGENT 南通科星化工有限公司 2021-03-04 WO disclosed
CN-1946747-B Polymer comprising amide and ester groups method for production and use thereof SIKA TECHNOLOGY AG 2010-11-24 CN disclosed
CN-1946747-A Polymer comprising amide and ester groups method for production and use thereof SIKA TECHNOLOGY AG (CH) 2007-04-11 CN disclosed
CN-1760347-A Power transmission fluids with enhanced antishudder durability AFTON CHEMICAL CORP (US) 2006-04-19 CN disclosed
US-6048885-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 2000-04-11 US disclosed