SCHEMBL21490423

SCHEMBL21490423

c1cn(N2CCCCCC2)cn1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 1/20 0.35
NFKB1 P19838 1/20 0.33
QPCT Q16769 1/20 0.33
HSD17B10 Q99714 1/20 0.33
QPCTL Q9NXS2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1268157 1.00 CYP2B6 (0.35) CYP2B6NFKB1QPCTHSD17B10QPCTL
SCHEMBL540364 0.98 NFKB1 (0.35) CYP2B6NFKB1QPCTHSD17B10QPCTL
Hydrochloric Acid SCHEMBL8473908 0.91 NFKB1 (0.33) CYP2B6NFKB1QPCTHSD17B10QPCTL
Pyrimidine SCHEMBL28401409 0.90 CYP1A2 (0.32) CYP2B6CYP1A2CYP3A4CYP2D6MAPT
SCHEMBL20445968 0.80 CHRNB2 (0.36)
SCHEMBL8129527 0.77 ADRB2 (0.36) NFKB1QPCTHSD17B10QPCTL
SCHEMBL8060339 0.77 NFKB1 (0.36) NFKB1QPCTHSD17B10QPCTLCYP1A2
SCHEMBL21047582 0.74 CYP11B1 (0.33) QPCT
SCHEMBL21047688 0.73 ACHE (0.32)
Fluoride SCHEMBL7489522 0.73 CYP1A2 (0.33) NFKB1QPCTHSD17B10QPCTLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110389502-B Electrophotographic member, process cartridge, and electrophotographic apparatus 佳能株式会社 2023-10-03 CN disclosed
US-10969709-B2 Member for electrophotography, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-04-06 US disclosed
CN-110389502-A Electrophotography component, handle box and electronic photographing device 佳能株式会社 2019-10-29 CN disclosed
US-20190324383-A1 MEMBER FOR ELECTROPHOTOGRAPHY, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2019-10-24 US disclosed