Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163972 | 0.93 | — | — | |
| SCHEMBL8724347 | 0.74 | CYP3A4 (0.45) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL2073935 | 0.71 | CYP11B2 (0.42) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL8726118 | 0.70 | CYP3A4 (0.45) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL16923117 | 0.69 | CYP3A4 (0.54) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL8724368 | 0.68 | CYP11B2 (0.44) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL27883558 | 0.68 | — | — | |
| SCHEMBL9481938 | 0.67 | MAPK1 (0.38) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8720924 | 0.67 | CYP3A4 (0.38) | CYP3A4MAPTLMNAENPP2MKNK1 | |
| SCHEMBL29026724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |
| US-6048885-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5246914-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| US-4447440-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |