Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073935 | 0.94 | CYP11B2 (0.42) | CYP11B2CYP11B1CYP3A4LMNAMAPT | |
| SCHEMBL27883558 | 0.85 | — | — | |
| SCHEMBL16323777 | 0.77 | CYP11B2 (0.41) | CYP11B2CYP11B1CYP3A4LMNAMAPT | |
| SCHEMBL29026724 | 0.76 | — | — | |
| SCHEMBL8724347 | 0.74 | CYP3A4 (0.45) | CYP11B2CYP11B1CYP3A4LMNAMAPT | |
| SCHEMBL16323717 | 0.72 | MAPT (0.48) | CYP11B2CYP11B1CYP3A4LMNAMAPT | |
| SCHEMBL5600749 | 0.72 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL29163972 | 0.70 | — | — | |
| SCHEMBL8726118 | 0.69 | CYP3A4 (0.45) | CYP11B2CYP11B1CYP3A4LMNAMAPT | |
| SCHEMBL16323988 | 0.69 | CYP11B2 (0.36) | CYP11B2CYP11B1CYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113215378-A | Anti-corrosion treatment method for low-alloy steel pipe of ship boiler | 哈尔滨锅炉厂有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |