Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058186 | 0.92 | HTR7 (0.49) | HTR7HTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL16212929 | 0.84 | CA1 (0.43) | — | |
| SCHEMBL23705003 | 0.79 | ALDH1A1 (0.56) | — | |
| SCHEMBL30058901 | 0.79 | ALDH1A1 (0.56) | — | |
| SCHEMBL8056407 | 0.78 | — | — | |
| SCHEMBL8062999 | 0.77 | HTR7 (0.49) | HTR7HTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL8060876 | 0.77 | HTR2B (0.48) | HTR7HTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL8057132 | 0.77 | HTR2B (0.46) | HTR7HTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL8062978 | 0.76 | HTR2B (0.45) | HTR7HTR2BDRD2ADRA1DHTR2A | |
| SCHEMBL8062875 | 0.76 | HTR7 (0.45) | HTR7HTR2BDRD2ADRA1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028069-A | Heterocyclyl-condensed benzoylguanidines, their production and use as inhibitors of the cellular Na+/H+-antiporter | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |