Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 16/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 16/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540005 | 1.00 | LMNA (0.57) | LMNATSHRALOX12HTTNPSR1 | |
| SCHEMBL4539041 | 0.95 | LMNA (0.60) | LMNATSHRALOX12HTTNPSR1 | |
| SCHEMBL4542200 | 0.90 | LMNA (0.54) | LMNAEPHX1EPHX2 | |
| SCHEMBL4542921 | 0.90 | CYP3A4 (0.57) | EPHX1EPHX2KMT2A | |
| SCHEMBL8062904 | 0.90 | EPHX2 (0.59) | EPHX1EPHX2 | |
| SCHEMBL4539891 | 0.89 | LMNA (0.65) | LMNATSHRALOX12HTTNPSR1 | |
| SCHEMBL4536850 | 0.89 | EPHX1 (0.52) | LMNAEPHX1EPHX2MEN1KMT2A | |
| SCHEMBL4541299 | 0.88 | EPHX1 (0.51) | LMNAEPHX1EPHX2 | |
| SCHEMBL4537586 | 0.88 | EPHX1 (0.52) | LMNATSHRHTTNPSR1EPHX1 | |
| SCHEMBL4535087 | 0.87 | EPHX1 (0.49) | LMNATSHRALOX12HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |