Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647160 | 0.79 | IL2 (0.46) | IL2MAPK1HCRTR1HCRTR2BACE1 | |
| SCHEMBL3097793 | 0.78 | IL2 (0.44) | IL2 | |
| SCHEMBL8055351 | 0.76 | IL2 (0.42) | IL2 | |
| SCHEMBL3103400 | 0.70 | RAB9A (0.45) | IL2 | |
| SCHEMBL8069094 | 0.68 | STIM1 (0.43) | IL2MAPK1 | |
| SCHEMBL3092144 | 0.68 | IL2 (0.46) | IL2 | |
| SCHEMBL3109398 | 0.67 | IL2 (0.41) | IL2 | |
| SCHEMBL5554286 | 0.66 | IL2 (0.69) | IL2 | |
| SCHEMBL2817751 | 0.64 | IL2 (0.69) | IL2 | |
| SCHEMBL11940274 | 0.63 | IL2 (0.41) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038775-A1 | SUBSTITUTED BENZOIMIDAZOLYL-PYRAZINE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2009-03-26 | — | — | WO | disclosed |