Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264501 | 0.85 | NCF1 (0.52) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL7356796 | 0.85 | NCF1 (0.47) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL16252851 | 0.85 | NCF1 (0.52) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL803131 | 0.81 | NCF1 (0.50) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL11904335 | 0.78 | NCF1 (0.47) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL26294685 | 0.78 | NCF1 (0.47) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL19053405 | 0.76 | LOXL2 (0.47) | NCF1LOXL2SSTR4MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7348696 | 0.76 | NCF1 (0.46) | NCF1LOXL2SSTR4MAPTNPC1 | |
| SCHEMBL14692676 | 0.76 | LOXL2 (0.44) | NCF1LOXL2SSTR4AAK1HTR1A | |
| SCHEMBL29393436 | 0.75 | NCF1 (0.44) | NCF1LOXL2SSTR4MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |