Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615106 | 0.85 | GAA (0.62) | GAAHTR2AHRH1HTR2CCYP2A13 | |
| SCHEMBL6195251 | 0.83 | DRD3 (0.55) | HTR2AHRH1HTR2CMEN1KMT2A | |
| SCHEMBL6258824 | 0.82 | GAA (0.46) | GAAHTR2AHTR2CDRD3DRD2 | |
| SCHEMBL6754937 | 0.78 | GAA (0.43) | GAAALDH1A1 | |
| SCHEMBL6754938 | 0.78 | GAA (0.43) | GAAALDH1A1 | |
| SCHEMBL6754941 | 0.78 | GAA (0.43) | GAAALDH1A1 | |
| SCHEMBL6194727 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HTR1A | |
| SCHEMBL7951734 | 0.74 | MTNR1A (0.55) | GAAMTNR1AHTR2A | |
| SCHEMBL9701340 | 0.74 | GAA (1.00) | GAACYP2A13ALDH1A1MEN1KMT2A | |
| SCHEMBL6194450 | 0.74 | HTR7 (0.57) | HTR2CMEN1KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013648-A | IMMUNOMODULATORS | SANOFI (FR) | 2000-01-11 | — | — | US | disclosed |
| WO-1997000860-A1 | CB2 RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |