Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653469 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL9432571 | 0.84 | CA1 (0.50) | ALDH1A1MAPTKDM4EHTTHPGD | |
| SCHEMBL9432437 | 0.84 | MAPT (0.61) | ALDH1A1MAPTKDM4EHTTLMNA | |
| SCHEMBL1983412 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL7807838 | 0.82 | TSHR (0.54) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL4013088 | 0.82 | TSHR (0.54) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL2048794 | 0.82 | TSHR (0.54) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL9723849 | 0.81 | DHODH (0.50) | ALDH1A1MAPTKDM4ETDP1HTT | |
| SCHEMBL9432803 | 0.79 | EPHX2 (0.44) | ALDH1A1MAPTKDM4ETDP1LMNA | |
| SCHEMBL9432414 | 0.78 | CES2 (0.44) | ALDH1A1MAPTKDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162945-A | Process for preparing 2-(2-methylphenyl)-3-methoxyacrylic acid methylester | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-19 | — | — | US | claimed |