Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4487426 | 0.82 | MEN1 (0.50) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL4487424 | 0.82 | MEN1 (0.50) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL962604 | 0.76 | ALDH1A1 (0.48) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL960634 | 0.74 | MAPT (0.61) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL960636 | 0.74 | MAPT (0.61) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL14264702 | 0.74 | GAA (0.41) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL12997974 | 0.73 | ATM (0.41) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL8269193 | 0.73 | CA12 (0.41) | GAATDP1NPSR1MAPTPOLB | |
| SCHEMBL26447626 | 0.71 | TSHR (0.45) | GAATDP1NPSR1MAPTPOLB | |
| Cyanide SCHEMBL28204276 | 0.71 | ALDH1A1 (0.44) | GAATDP1NPSR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076454-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2009-06-18 | — | — | WO | disclosed |