SCHEMBL80625

SCHEMBL80625

O=C(O)C1SC(=S)NC1=O

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.45
CA2 P00918 3/20 0.42
TSHR P16473 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
EGLN1 Q9GZT9 1/20 0.30
TOP2A P11388 1/20 0.30
SLC22A12 Q96S37 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14397335 0.67
SCHEMBL3066557 0.63 CA2 (0.67) PSMD14CA2TSHRKDM4E
SCHEMBL16824544 0.62
SCHEMBL29167393 0.60 ALDH1A1 (0.43) TSHR
SCHEMBL2761339 0.59
SCHEMBL5658359 0.59
SCHEMBL10833048 0.58 MAP2K1 (0.45) TSHRHTT
SCHEMBL11373401 0.55 HSD17B10 (0.50) TSHRKDM4EHTTTOP2ASLC22A12
SCHEMBL6279062 0.55
Bicarbonate SCHEMBL9560502 0.53 IDUA (0.41) CA2TSHRKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779896-B2 Magnetic-optical composite nanostructure KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2023-10-10 US claimed
EP-3514177-B1 ANTIBODY SPECIFICALLY BINDING TO PD-1 AND FUNCTIONAL FRAGMENT THEREOF Beijing hanmi pharm co ltd (CN) 2023-07-26 EP claimed
US-20230201380-A1 NON-INVASIVE AND LONGITUDINAL MONITORING OF MICROGLIAL ACTIVATION IN RAT BRAIN WITH SUPERMAGNETIC NANOPARTICLE ENHANCED MR IMAGING UNM RAINFOREST INNOVATIONS (US) 2023-06-29 US claimed
CN-109627338-B Novel anti-human PD-L1 antibody and application thereof 苏州药明泽康生物科技有限公司 2022-10-18 CN claimed
US-20220146431-A1 REAGENTS AND METHODS FOR DETECTING INFECTIOUS DISEASES IONICA SCIENCES 2022-05-12 US claimed
EP-3514176-B1 ANTIBODY SPECIFICALLY BINDING TO IL-17A AND FUNCTIONAL FRAGMENT THEREOF BEIJING HANMI PHARMACEUTICAL CO LTD (CN) 2021-12-15 EP claimed
WO-2021242896-A1 NON-INVASIVE AND LONGITUDINAL MONITORING OF MICROGLIAL ACTIVATION IN RAT BRAIN WITH SUPERMAGNETIC NANOPARTICLE ENHANCED MR IMAGING UNM RAINFOREST INNOVATIONS (US) 2021-12-02 WO claimed
EP-3875599-A1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Astellas Institute for Regenerative Medicine (US) 2021-09-08 EP claimed
CN-110483643-B Novel antibody composition, isolated nucleic acid and preparation method 深圳市雅为泓源生物科技有限公司 2021-06-08 CN claimed
EP-2596119-B1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ASTELLAS INST FOR REGENERATIVE MEDICINE (US) 2021-04-28 EP claimed
US-6855503-B2 Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing AMERSHAM BIOSCIENCES CORP (US) 2005-02-15 US claimed
WO-2004059011-A1 HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING AMERSHAM BIOSCIENCES CORP (US) 2004-07-15 WO claimed
US-20040126763-A1 Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing GE HEALTHCARE BIO-SCIENCES CORP. 2004-07-01 US claimed
WO-2004029578-A2 ENERGY TRANSFER DYES, TERMINATORS AND USE THEREOF AMERSHAM BIOSCIENCES CORP (US) 2004-04-08 WO claimed
WO-2004029579-A2 FLUORESCENT LABELING REAGENTS WITH MULTIPLE DONORS AND ACCEPTORS AMERSHAM BIOSCIENCES CORP (US) 2004-04-08 WO claimed
JP-2002523783-A 2002-07-30 JP claimed
EP-1110088-A1 ENERGY TRANSFER DYES Amersham Pharmacia Biotech Inc (US) 2001-06-27 EP claimed
WO-2000013026-A9 ENERGY TRANSFER DYES AMERSHAM PHARM BIOTECH INC (US) 2000-08-17 WO claimed
WO-2000013026-A1 ENERGY TRANSFER DYES AMERSHAM PHARMACIA BIOTECH, INC. (US) 2000-03-09 WO claimed
US-5863727-A AN ACCEPTOR FLUOROPHORE EFFICIENTLY ABSORBS ENERGY EMISSION OF A LINKED DONOR XANTHENE FLUOROPHORE LABELLING A OLIGONUCLEOTIDE PRIMER; REAGENT FOR SEQUENCING NUCLEIC ACIDS THE PERKIN-ELMER CORPORATION 1999-01-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040126763-A1 Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing DNTT, POLL, POLRMT PSMD14 2733/4885CA2 4796/4885TSHR 2059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.