SCHEMBL8062604

SCHEMBL8062604

Nc1cc(C(c2ccc(O)c(N)c2)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.59
GAA P10253 8/20 0.59
MAPT P10636 4/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
RECQL P46063 2/20 0.59
PKM P14618 2/20 0.59
HSD17B10 Q99714 6/20 0.48
ALOX15 P16050 6/20 0.48
HPGD P15428 4/20 0.48
ALOX12 P18054 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MAPK1 P28482 1/20 0.48
CHEK1 O14757 1/20 0.44
FYN P06241 1/20 0.44
PDGFRB P09619 1/20 0.44
PIM1 P11309 1/20 0.44
FGFR1 P11362 1/20 0.44
FLT1 P17948 1/20 0.44
GRK5 P34947 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9308489 0.83 ALDH1A1 (0.63) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL26579 0.79 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29379543 0.79 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29360962 0.79 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL19075862 0.78 ALDH1A1 (0.75) ALDH1A1GAAMAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL48746 0.78 ALDH1A1 (0.57) ALDH1A1GAAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL8977755 0.78 ALDH1A1 (0.57) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL14476250 0.75 ALDH1A1 (0.53) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29412585 0.74 ALDH1A1 (0.76) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29555588 0.74 ALDH1A1 (0.76) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077928-A Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-06-20 US disclosed
US-6031061-A Bis (triaklyltrimellitic anhydride) derivative and polyesterimide for optical communications formed therefrom SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-02-29 US disclosed