Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464161 | 0.92 | CYP1A1 (0.53) | GSK3BXDHCYP3A4TP53CYP19A1 | |
| SCHEMBL773768 | 0.90 | CYP19A1 (0.47) | GSK3BXDHCYP3A4TP53CYP19A1 | |
| SCHEMBL13829395 | 0.86 | CDK1 (0.44) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL1164995 | 0.86 | ALDH1A1 (0.50) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL1164884 | 0.86 | ALDH1A1 (0.50) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL5084285 | 0.86 | CYP19A1 (0.44) | GSK3BXDHCYP3A4TP53CYP19A1 | |
| SCHEMBL2319151 | 0.85 | CYP19A1 (0.57) | GSK3BXDHCYP3A4TP53CYP19A1 | |
| SCHEMBL12573073 | 0.85 | CDK1 (0.44) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL6509060 | 0.84 | CYP1A1 (0.56) | GSK3BXDHCYP3A4TP53CYP19A1 | |
| SCHEMBL8066879 | 0.82 | GSK3B (0.46) | GSK3BCDK1CCNB1GSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |