Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.42 |
| ▸ | TUBB | P07437 | 6/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382209 | 0.87 | TUBB4A (0.47) | GSK3BXDHTUBB4ATUBBTUBA3C | |
| SCHEMBL27775453 | 0.87 | NPC1 (0.44) | GSK3BXDHHDAC6NPC1RAB9A | |
| SCHEMBL28552152 | 0.85 | NPC1 (0.55) | NPC1RAB9AMAPK14CYP19A1MAPT | |
| SCHEMBL7605697 | 0.84 | XDH (0.42) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL29186041 | 0.83 | CDK1 (0.44) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL4129050 | 0.83 | CDK1 (0.47) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL8063267 | 0.82 | GSK3B (0.49) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL8064381 | 0.82 | CDK1 (0.45) | GSK3BCDK1CCNB1GSK3ACDK5 | |
| SCHEMBL4218778 | 0.82 | ACHE (0.45) | NPC1RAB9AACHECYP3A4CYP19A1 | |
| SCHEMBL13829395 | 0.79 | CDK1 (0.44) | GSK3BCDK1CCNB1GSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |