Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL15103152 | 0.86 | FDPS (0.43) | HSP90AB1HSP90AA1ALDH1A1SMN1; SMN2LMNA | |
| Phosphoric Acid SCHEMBL5961216 | 0.86 | LMNA (0.42) | SMN1; SMN2LMNACYP1A2 | |
| Phosphoric Acid SCHEMBL7765511 | 0.86 | LMNA (0.42) | SMN1; SMN2LMNACYP1A2 | |
| Phosphoric Acid SCHEMBL10873614 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL4801853 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL670321 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL752823 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL407305 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL73239 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 | |
| Phosphoric Acid SCHEMBL28199623 | 0.86 | CYP1A2 (0.42) | SMN1; SMN2LMNACYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6146557-A | Fire resistant resin composition | TOKUYAMA CORPORATION (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0877048-A2 | Fire resistant resin composition | TOKUYAMA CORPORATION (JP) | 1998-11-11 | — | — | EP | disclosed |