Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059119 | 0.90 | MAPT (0.59) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8069707 | 0.87 | PTPN1 (0.50) | MAPTPTPN1MTORCNR2ALDH1A1 | |
| SCHEMBL8074725 | 0.87 | MAPT (0.63) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8073121 | 0.87 | MAPT (0.57) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8069963 | 0.86 | TAS2R14 (0.64) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8069684 | 0.85 | TAS2R14 (0.65) | MAPTTAS2R14CNR2CXCR3PTGES | |
| SCHEMBL8059346 | 0.84 | MAPT (0.51) | MAPTTAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL8070323 | 0.83 | MAPT (0.52) | MAPTTAS2R14MEN1KMT2ACNR2 | |
| SCHEMBL8083933 | 0.82 | MAPT (0.51) | MAPTTAS2R14MEN1KMT2ACXCR3 | |
| SCHEMBL8070251 | 0.82 | MAPT (0.56) | MAPTTAS2R14MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017685-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL-PRODESFARMA, S.A. (ES) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999014205-A1 | NEW 2-(3H)-OXAZOLONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 1999-03-25 | — | — | WO | disclosed |