SCHEMBL8064200

SCHEMBL8064200

CCC(C)Oc1ccc(CCC(C)C(=O)O)cc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.51
PPARD Q03181 8/20 0.51
PPARA Q07869 7/20 0.51
DHODH Q02127 1/20 0.42
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
LTB4R Q15722 1/20 0.39
S1PR1 P21453 2/20 0.38
MAPT P10636 1/20 0.38
PDE4A P27815 3/20 0.38
PDE4B Q07343 3/20 0.38
PDE4C Q08493 3/20 0.38
PDE4D Q08499 3/20 0.38
PTPN1 P18031 1/20 0.38
S1PR3 Q99500 1/20 0.37
S1PR5 Q9H228 1/20 0.37
CD274 Q9NZQ7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27427443 0.92 PPARG (0.52) PPARGPPARDPPARAPTGER1PTGER4
SCHEMBL27406917 0.84 PPARG (0.43) PPARGPPARDPPARAPTGER1PTGER4
SCHEMBL7724922 0.83 PPARD (0.56) PPARGPPARDPPARADHODHS1PR1
SCHEMBL27430018 0.82 PPARG (0.48) PPARGPPARDPPARAPTGER1PTGER4
SCHEMBL27406192 0.82 PTGER1 (0.45) PPARGPPARDPPARADHODHPTGER1
SCHEMBL27406919 0.81 THRA (0.51) PPARGPPARDPPARAPTGER1PTGER4
SCHEMBL27403100 0.81 PPARG (0.46) PPARGPPARDPPARAPTGER1PTGER4
SCHEMBL7735357 0.81 PTPN1 (0.50) PPARGPPARDPPARADHODHPDE4A
SCHEMBL27425815 0.78 PDE4A (0.43) PTGER1PTGER4PTGER3PTGER2PDE4A
SCHEMBL27427441 0.77 PDE4A (0.42) PTGER1PTGER4PTGER3PTGER2PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103332-C Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2003-03-19 CN disclosed
CN-1276778-A Biphenyl-5-alkanoic acid derivs. and use thereof ASAHI CHEMICAL IND (JP) 2000-12-13 CN disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed