Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.56 |
| ▸ | PPARG | P37231 | 8/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735398 | 0.91 | PPARG (0.59) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL7735357 | 0.90 | PTPN1 (0.50) | PPARDPPARGPPARAHDAC1SMN1; SMN2 | |
| SCHEMBL7735870 | 0.84 | PPARD (0.47) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL8064200 | 0.83 | PPARG (0.51) | PPARDPPARGPPARAS1PR1S1PR3 | |
| SCHEMBL7734077 | 0.82 | PPARD (0.47) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL7725085 | 0.81 | PPARG (0.45) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL7737531 | 0.81 | PPARG (0.52) | PPARDPPARGPPARADHODH | |
| SCHEMBL7724925 | 0.81 | THRA (0.52) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL7725133 | 0.80 | PPARD (0.52) | PPARDPPARGPPARACYP1A2PLA2G10 | |
| SCHEMBL7725029 | 0.80 | CYP1A2 (0.52) | PPARDPPARGPPARACYP1A2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | claimed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | claimed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | claimed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | claimed |
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |